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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 905111Generated: October 25, 2026

Novoldiamine → Chloroquine

https://huagongshe.com/reaction/905111

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNovoldiamineHCID 78953—
Reactant7-Chloro-1,2,3,4-tetrahydroquinolin-2-oneHCID 13690766—
ProductChloroquineHCID 271990%

Reaction Steps

3.665 millimols, i.e. a yield of 90% relative to the 7-chloro-1,2,3,4-tetrahydroquinolinone converted, and a yield of 91.2% relative to the 1-diethylamino-4-aminopentane converted, and

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04421920
Source datasetuspto-grants-1983_12
ORD IDord-c5729567dac1469fbcb1cae3d5b87980
Source noteuspto-grants-1983_12