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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 905112Generated: October 25, 2026

Novoldiamine → Chloroquine

https://huagongshe.com/reaction/905112

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNovoldiamineHCID 78953—
Reactant7-Chloro-2,3-dihydro-4-quinoloneHCID 88974—
ProductChloroquineHCID 271994.9%

Reaction Steps

19.116 millimols, i.e. a yield of 94.9% relative to the 7-chloro-1,2,3,4-tetrahydroquinolin-4-one converted, and a yield of 97.5% relative to the 1-diethylamino-4-amino-pentane converted, and

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04421920
Source datasetuspto-grants-1983_12
ORD IDord-db363da9f2064cba9ba78b1b4ac1fa53
Source noteuspto-grants-1983_12