Triethyl phosphite → Phosphonic acid, [(formylamino)methyl]-, diethyl ester

HRID 905161Notes

Reaction equation

O[CH2:2][NH:3][CH:4]=[O:5].[CH2:6]([O:8][P:9]([O:13]CC)[O:10][CH2:11][CH3:12])[CH3:7]>>[CH2:6]([O:8][P:9]([CH2:2][NH:3][CH:4]=[O:5])(=[O:13])[O:10][CH2:11][CH3:12])[CH3:7]

Participants

Reactant 2

HCID 31215Triethyl phosphite

HCID 83086Formamide, N-(hydroxymethyl)-

Product 1

HCID 12673118Phosphonic acid, [(formylamino)methyl]-, diethyl ester

Procedure

reaction of N-(hydroxymethyl)formamide with triethylphosphite with accompanying heat, to form diethyl-N-(formyl)aminomethylphosphonate,

Sources & evidence

ORD record: ord-ea27b0b7da024c5d9b7c65a7cc1bee65
Source dataset: uspto-grants-1983_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04422982

Reaction notes

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