Hydrogen Peroxide → HCID 12958934, compound

Participants

Reaction Steps

30% Hydrogen peroxide (50 mmol) was added to a solution of 2-allylthio-5-chloropyrimidine (10 mmol) in acetic acid (15 ml) and the mixture stirred at room temperature for 24 h. The resultant solution was concentrated at reduced pressure to a small volume, water (20 ml) added and the mixture extracted with chloroform, the chloroform solution washed with potassium carbonate solution, the dried (MgSO4) solution evaporated and the residue crystallized from chloroform: pet. ether; yield 78%, m.p. 82° C. 1H NMR (CDCl3): δ3.7-4.0 (CH2, 5.0-6.2 (3H, CH2 =CH), 8.86 (H-4, H-6).

Provenance & Evidence