2-Chloroethyl isocyanate → HCID 13254209, compound

Participants

Reaction Conditions

Reaction Steps

Neopentylamine (8.7 g, 0.1 mol) was dissolved in 50 ml of anhydrous diethyl ether and cooled to 5° C. 2-Chloroethyl isocyanate (10.5 g, 0.1 mol) dissolved in an additional 50 ml of ether was added over 30 minutes while maintaining a temperature of less than 10° C. Stirring continued for an additional hour, and the cold mixture was filtered and washed with chilled ether. The compound was dried in a desiccator over sodium hydroxide overnight giving 15.4 g (80%) as a white powder, MP (melting point) 90°-1° C. (decomposes). Elemental analysis showed the following:

Provenance & Evidence