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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 905313Generated: October 29, 2026

Diethyl (ethoxymethylene)malonate → HCID 5159075, compound

https://huagongshe.com/reaction/905313

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl (ethoxymethylene)malonateHCID 6871—
Reactant4-tert-Butyl-1,3-thiazol-2-amineHCID 2734202—
ProductHCID 5159075HCID 5159075—

Reaction Steps

2-Amino-4-(2-methyl-2-propyl)thiazole (15.6 g., 0.1 mole) and diethyl ethoxymethylenemalonate (23.8 g., 0.11 mole) were combined and heated on a steam bath for 2 hours. 2-(2,2-Dicarbethoxyethenylamino)-4-(2-methyl-2-propyl) thiazole was obtained as a wet solid on cooling and used directly in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04423048
Source datasetuspto-grants-1983_12
ORD IDord-c128d4d6a68848969412f1807763f8af
Source noteuspto-grants-1983_12