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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 9055Generated: October 25, 2026

Dimethylamine → 3-[(2,3-Dimethoxy-phenyl)-dimethylamino-methyl]-4,7-dihydro-1H-indole-6-carboxylic Acid

https://huagongshe.com/reaction/9055

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant2,3-DimethoxybenzaldehydeHCID 66581—
Reactant1H-indole-6-carboxylic acidHCID 595230—
Reactant(2,3-Dimethoxy-benzylidene)-dimethylammonium chlorideHCID 21985319—
Product3-[(2,3-Dimethoxy-phenyl)-dimethylamino-methyl]-4,7-dihydro-1H-indole-6-carboxylic AcidHCID 21985346—

Reaction Steps

The preparation was carried out in accordance with general synthesis instructions 4 from 1H-indole-6-carboxylic acid and (2,3-dimethoxy-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 2,3-dimethoxy-benzaldehyde and dimethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091220B2
Source datasetuspto-grants-2006_08
ORD IDord-354e6617f7a94d3ab81859a0b3502e64
Source noteuspto-grants-2006_08