HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dibromoethane → Methyl {3-[(2-bromoethyl)amino]phenyl}acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dibromoethane | HCID 7839 | — |
| Reactant | Methyl 3-aminophenylacetate | HCID 13054266 | — |
| Product | Methyl {3-[(2-bromoethyl)amino]phenyl}acetate | HCID 58552026 | — |
Reaction Steps
Methyl (3-aminophenyl)acetate (1 g) and 1,2-dibromoethane (5 ml) were heated at 100° C. for 5 hours. After cooling, the resultant was purified by column chromatography (ethyl acetate: isohexane 7:3) to give the titled compound as an oil. Yield: 280 mg (17%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08012964B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-292b04430b954ba9b840eeea5004ae5e |
| Source note | uspto-grants-2011_09 |