HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 23071585, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Iodo-4-nitrobenzene | HCID 12495 | — |
| Reactant | Calcium Chloride | HCID 5284359 | — |
| Reactant | 5-Oxo-(1,4)diazepane-1-carboxylic acid tert-butyl ester | HCID 22617736 | — |
| Catalyst | Copper | HCID 23978 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | 1,2-Dichlorobenzene | HCID 7239 | — |
| Product | HCID 23071585 | HCID 23071585 | — |
Reaction Steps
4-Iodonitrobenzene and tert-butyl 5-oxo-[1,4]diazepan-1-carboxylate were allowed to undergo the reaction in 1,2-dichlorobenzene in the presence of copper powder and potassium carbonate, and then the nitro group was reduced in ethanol using zinc powder and calcium chloride to obtain benzyl 4-(4-aminophenyl)-5-oxo-1,4-diazepan-1-carboxylate. ESI: 340.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08012959B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-57ddea77910f4519848e53cb25c4b4e5 |
| Source note | uspto-grants-2011_09 |