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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 905744Generated: October 31, 2026

N-(2-oxoindolin-5-yl)acetamide → HCID 66612530, compound

https://huagongshe.com/reaction/905744

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2-oxoindolin-5-yl)acetamideHCID 11206280—
Reactant3-methyl-5-(2-morpholin-4-yl-ethyl)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehydeHCID 86637676—
ProductHCID 66612530HCID 6661253071.2%

Reaction Steps

The title compound was prepared under the same conditions as described in Example 15 with 3-methyl-5-(2-morpholin-4-yl-ethyl)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehyde and N-(2-oxo-2,3-dihydro-1H-indol-5-yl)-acetamide as starting materials to give N-{3-[3-methyl-5-(2-morpholin-4-yl-ethyl)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indol-5-yl}-acetamide (60 mg, 71.2%) as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08012966B2
Source datasetuspto-grants-2011_09
ORD IDord-e38cf78ca0294a71853bd115d286fe9a
Source noteuspto-grants-2011_09