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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 905765Generated: October 29, 2026

4-(2-Hydroxyethyl)indolin-2-one → HCID 66607928, compound

https://huagongshe.com/reaction/905765

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Hydroxyethyl)indolin-2-oneHCID 10943004—
Reactant5-(2-diethylaminoethyl)-3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehydeHCID 25023015—
ProductHCID 66607928HCID 6660792835%

Reaction Steps

The title compound was prepared under the same conditions as described in Example 1 with 5-(2-diethylamino-ethyl)-3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehyde and 4-(2-hydroxy-ethyl)-1,3-dihydro-indol-2-one (prepared according to US2004186160) as starting materials to give 5-(2-diethylamino-ethyl)-2-[4-(2-hydroxy-ethyl)-2-oxo-1,2-dihydro-indol-3-ylidenemethyl]-3-methyl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one (30 mg, 35.0%) as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08012966B2
Source datasetuspto-grants-2011_09
ORD IDord-e37d12307765459eb1ddf884de5de574
Source noteuspto-grants-2011_09