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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 905768Generated: October 30, 2026

5-Bromo-2-oxindole → HCID 66608061, compound

https://huagongshe.com/reaction/905768

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-oxindoleHCID 611193—
Reactant5-(2-diethylaminoethyl)-3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehydeHCID 25023015—
ProductHCID 66608061HCID 6660806194.2%

Reaction Steps

The title compound was prepared under the same conditions as described in Example 1 with 5-(2-diethylamino-ethyl)-3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehyde and 5-bromo-1,3-dihydro-indol-2-one as starting materials to give 2-(5-bromo-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-3-methyl-5-(2-pyrrolidin-1-yl-ethyl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one (1.33 g, 94.2%) as an orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08012966B2
Source datasetuspto-grants-2011_09
ORD IDord-42572193d3fe43beba96f35f1a1e3c38
Source noteuspto-grants-2011_09