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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 905809Generated: October 29, 2026

4-bromo-2,3-dihydro-1H-indol-2-one → HCID 66608410, compound

https://huagongshe.com/reaction/905809

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-bromo-2,3-dihydro-1H-indol-2-oneHCID 2763190—
Reactant3-methyl-4-oxo-5-(2-pyrrolidin-1-yl-ethyl)-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehydeHCID 86637675—
ProductHCID 66608410HCID 6660841074.4%

Reaction Steps

The title compound was prepared under the same conditions as described in Example 13 with 3-methyl-4-oxo-5-(2-pyrrolidin-1-yl-ethyl)-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehyde and 4-bromo-1,3-dihydro-indol-2-one (prepared according to US20030225127) as starting materials to give 2-(4-bromo-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-3-methyl-5-(2-pyrrolidin-1-yl-ethyl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one (44 mg, 74.4%) as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08012966B2
Source datasetuspto-grants-2011_09
ORD IDord-561a872a41d24a2dac7466203a047fcc
Source noteuspto-grants-2011_09