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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 905810Generated: October 29, 2026

4-Methyl-1,3-dihydro-2H-indol-2-one → HCID 66607131, compound

https://huagongshe.com/reaction/905810

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methyl-1,3-dihydro-2H-indol-2-oneHCID 12579382—
Reactant3-methyl-4-oxo-5-(2-pyrrolidin-1-yl-ethyl)-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehydeHCID 86637675—
ProductHCID 66607131HCID 6660713162.8%

Reaction Steps

The title compound was prepared under the same conditions as described in Example 13 with 3-methyl-4-oxo-5-(2-pyrrolidin-1-yl-ethyl)-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehyde and 4-methyl-1,3-dihydro-indol-2-one (prepared according to U.S. Pat. No. 6,114,371) as starting materials to give 3-methyl-2-(4-methyl-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-5-(2-pyrrolidin-1-yl-ethyl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one (32 mg, 62.8%) as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08012966B2
Source datasetuspto-grants-2011_09
ORD IDord-a5d5b41c37c54f1894d7f929635bf429
Source noteuspto-grants-2011_09