HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67386154, compound → (3R,4S)-3-Methyl-1-(methylsulfonyl)piperidin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67386154 | HCID 67386154 | — |
| Reactant | (3S,4S)-3-Methyltetrahydro-2H-pyran-4-amine hydrochloride | HCID 126970408 | — |
| Product | (3R,4S)-3-Methyl-1-(methylsulfonyl)piperidin-4-amine | HCID 95778702 | — |
Reaction Steps
Racemic cis 1-methanesulfonyl-3-methyl-piperidin-4-yl-amine was prepared in the same manner from racemic benzyl-(1-methanesulfonyl-3-methyl-piperidin-4-yl)-amine. In this instance, 1 atm H2 was used instead of 55 psi, and the HCl treatment was omitted.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08012974B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-3f026960a77649f6a42a42eeeaf15813 |
| Source note | uspto-grants-2011_09 |