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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 905936Generated: October 31, 2026

Hydrochloric Acid → HCID 124523402, compound

https://huagongshe.com/reaction/905936

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 131729151HCID 131729151—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
ProductHCID 124523402HCID 124523402—

Reaction Steps

Racemic cis 4-amino-5-methyl-azepane-1-carboxylic acid tert-butyl ester was prepared in the same manner from racemic cis 4-benzylamino-5-methyl-azepane-1-carboxylic acid tert-butyl ester. In this instance, 1 atm H2 was used instead of 55 psi, Pd/C was used instead of Pd(OH)2/C, EtOAc was used instead of EtOH, and the HCl treatment was omitted.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08012974B2
Source datasetuspto-grants-2011_09
ORD IDord-d01508f1a51d42a8903426a99707a6e9
Source noteuspto-grants-2011_09