Benzylamine → HCID 131729154, compound

HRID 905939Notes

Reaction equation

HRID 905939 reaction equation
[CH3:1][O:2][C:3]([N:5]1[CH2:10][CH2:9][C:8](=O)[CH:7]([CH3:12])[CH2:6]1)=[O:4].[CH2:13]([NH2:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH3:1][O:2][C:3]([N:5]1[CH2:10][CH2:9][C@H:8]([NH:20][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C@H:7]([CH3:12])[CH2:6]1)=[O:4]

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 3015586Methyl 3-methyl-4-oxopiperidine-1-carboxylate

Product 1

HCID 131729154HCID 131729154, compound

Procedure

Racemic cis 4-benzylamino-3-methyl-piperidine-1-carboxylic acid methyl ester was prepared in the same manner from racemic 3-methyl-4-oxo-piperidine-1-carboxylic acid methyl ester. In this instance, benzylamine was used instead of (R)-1-phenylethylamine.

Sources & evidence

ORD record
ord-876a1bf294274d7ea2cceadf78b83574
Source dataset
uspto-grants-2011_09
Patent number
US08012974B2

Reaction notes

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