HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → 5-Methylazepan-4-One Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | HCID 20594186 | HCID 20594186 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 5-Methylazepan-4-One Hydrochloride | HCID 67385268 | — |
Reaction Steps
A solution of 4-methyl-5-oxo-azepane-1-carboxylic acid tert-butyl ester (700 mg, 3.083 mmol) was dissolved in 10% TFA in DCM (30 mL) and stirred at RT for 6 hours before being evaporated to give 0.74 g of 5-methyl-azepan-4-one hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08012974B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-83bde626cdc44d4082903f2e2350d34f |
| Source note | uspto-grants-2011_09 |