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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 906016Generated: October 27, 2026

Ethanesulfonyl chloride → 1-[(1-Ethane sulfonyl)-piperidin-3-yl]-3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-urea

https://huagongshe.com/reaction/906016

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanesulfonyl chlorideHCID 11667—
Reactant1-piperidin-3-yl-3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-urea dihydrochlorideHCID 67385590—
Product1-[(1-Ethane sulfonyl)-piperidin-3-yl]-3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-ureaHCID 67386299—

Reaction Steps

1-[(1-Ethane sulfonyl)-piperidin-3-yl]-3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-urea was prepared in the same manner from 1-piperidin-3-yl-3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-urea dihydrochloride and ethanesulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08012974B2
Source datasetuspto-grants-2011_09
ORD IDord-f0b50ca6af004615829b85e79a626d50
Source noteuspto-grants-2011_09