Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 906018Generated: October 26, 2026

Cyclopropanesulfonyl chloride → 1-(1-Cyclopropylsulfonyl-piperidin-3-yl)-3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-urea

https://huagongshe.com/reaction/906018

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanesulfonyl chlorideHCID 2760919—
Reactant1-piperidin-3-yl-3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-urea dihydrochlorideHCID 67385590—
Product1-(1-Cyclopropylsulfonyl-piperidin-3-yl)-3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-ureaHCID 67385452—

Reaction Steps

1-(1-Cyclopropylsulfonyl-piperidin-3-yl)-3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-urea was prepared in the same manner from 1-piperidin-3-yl-3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-urea dihydrochloride and cyclopropylsulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08012974B2
Source datasetuspto-grants-2011_09
ORD IDord-72c3e74c1f3b49679ca638eb5d944c22
Source noteuspto-grants-2011_09