Acetone → 1-(Propan-2-yl)piperidin-4-amine

HRID 906076Notes

Reaction equation

HRID 906076 reaction equation
[NH:1]1[CH2:6][CH2:5][CH:4]([NH:7]C(=O)OC(C)(C)C)[CH2:3][CH2:2]1.[CH3:15][C:16]([CH3:18])=O>>[CH3:15][CH:16]([N:1]1[CH2:2][CH2:3][CH:4]([NH2:7])[CH2:5][CH2:6]1)[CH3:18]

Participants

3

Reactant 2

HCID 180AcetoneHCID 7238334-(N-Boc-amino)piperidine

Product 1

HCID 31633331-(Propan-2-yl)piperidin-4-amine

Procedure

Synthesized according to the method of reagent preparation 9 by using acetone and 1,1-dimethylethyl piperidin-4-ylcarbamate. MS (EI) for C8H18N2: 143 (MH+).

Workup

  1. customSynthesized
  2. customaccording to the method of reagent preparation 9

Sources & evidence

ORD record
ord-80882484485d49c68e66052e17746548
Source dataset
uspto-grants-2011_09
Patent number
US08012956B2

Reaction notes

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