3-[(Piperidin-4-yl)amino]benzonitrile → HCID 43345827, compound

HRID 906355Notes

Reaction equation

HRID 906355 reaction equation
[NH2:1][C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][CH:11]1[CH2:16][CH2:15][N:14](C(OC(C)(C)C)=O)[CH2:13][CH2:12]1)=[O:3].N1CCC(NC2C=C(C=CC=2)C#N)CC1>>[NH:14]1[CH2:13][CH2:12][CH:11]([NH:10][C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[C:2]([NH2:1])=[O:3])[CH2:16][CH2:15]1

Participants

3

Procedure

The title compound was prepared from 1,1-dimethylethyl 4-{[2-(aminocarbonyl)phenyl]amino}-1-piperidinecarboxylate (D19) using a method similar to that described for D6 in Description 6.

Sources & evidence

ORD record
ord-05b7b0f4f72949858474d827e653c559
Source dataset
uspto-grants-2011_09
Patent number
US08012981B2

Reaction notes

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