反应详情

5 g of 3,5-difluorophenylacetic acid are dissolved in 50 ml of ethanol and 3 ml of concentrated H2SO4, and the mixture is heated at reflux for two hours. The mixture is evaporated to dryness, neutralization is then carried out with a saturated K2CO3 solution, extraction is then carried out with AcOEt and the organic phase is evaporated to produce 5.0 g of the expected compound in the form of a colourless liquid.

1. temperatureat reflux for two hours
2. customThe mixture is evaporated to dryness, neutralization
3. extractionis then carried out with a saturated K2CO3 solution, extraction
4. customthe organic phase is evaporated