Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 906793Generated: October 25, 2026

3-[(Thiophen-2-ylmethyl)-amino]-phthalic acid dimethyl ester → 3-[(Thiophen-2-ylmethyl)-amino]-phthalic acid

https://huagongshe.com/reaction/906793

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[(Thiophen-2-ylmethyl)-amino]-phthalic acid dimethyl esterHCID 21040138—
Reactant3-(2-Methoxy-ethylamino)-phthalic acidHCID 21988519—
Product3-[(Thiophen-2-ylmethyl)-amino]-phthalic acidHCID 21988596—

Reaction Steps

3-[(Thiophen-2-ylmethyl)-amino]-phthalic acid dimethyl ester (0.88 g, 2.88 mmol) was treated in the same manner as described above for the synthesis 3-(2-methoxy-ethylamino)-phthalic acid. The product of the reaction, which contained a mixture of diacid and monomethyl esters, was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08012997B2
Source datasetuspto-grants-2011_09
ORD IDord-0ff03dfa3df742909a41335251af7860
Source noteuspto-grants-2011_09