反应详情

By an operation in the same manner as in Example 1 and using (2S,3S)-2-methyl-3-(trifluoromethyl)pyrrolidin-3-ol 0.5 oxalate (200 mg), 2,4-difluorobenzonitrile (258 mg) and lithium carbonate (138 mg), the title compound was obtained as a colorless solid (yield: 120 mg, yield: 45%).