反应详情

By an operation in the same manner as in Example 1 and using (2S,3S)-3-ethyl-2-isopropylpyrrolidin-3-ol 0.5 oxalate (162 mg), 2,4-difluorobenzonitrile (112 mg) and lithium carbonate (126 mg), the title compound was obtained as colorless oil (yield: 136 mg, yield: 62%).