反应详情

By an operation in the same manner as in Example 1 and using (2S,3R)-3-cyclopropyl-2-isopropylpyrrolidin-3-ol 0.5 oxalate (215 mg), 2-chloro-4-fluorobenzonitrile (156 mg) and lithium carbonate (163 mg), the title compound was obtained as a pale-brown solid (yield: 130 mg, yield: 43%).