反应详情

By an operation in the same manner as in Example 1 and using (2S,3R)-3-cyclopropyl-2-methylpyrrolidin-3-ol 0.5 oxalate (200 mg), 2,4-difluorobenzonitrile (255 mg) and lithium carbonate (180 mg), the title compound was obtained as a colorless solid (yield: 188 mg, yield: 59%).