反应详情

By an operation in the same manner as in Example 1 and using (2S,3R)-3-cyclopropyl-2-methylpyrrolidin-3-ol 0.5 oxalate (200 mg), 2-methoxy-4-fluorobenzonitrile (277 mg) and lithium carbonate (180 mg), the title compound was obtained as a pale-yellow solid (yield: 192 mg, yield: 58%).