HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Carbonate → HCID 59273062, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Carbonate | HCID 11125 | — |
| Reactant | 2-Chloro-4-fluoro-3-methylbenzonitrile | HCID 44550971 | — |
| Reactant | (2S,3R)-3-cyclopropyl-2-isopropylpyrrolidin-3-ol | HCID 59273011 | — |
| Product | HCID 59273062 | HCID 59273062 | — |
Reaction Steps
By an operation in the same manner as in Example 1 and using (2S,3S)-2-ethyl-3-methylpyrrolidin-3-ol 0.5 oxalate (210 mg), 2-chloro-4-fluoro-3-methylbenzonitrile (300 mg) and lithium carbonate (215 mg), the title compound was obtained as pale-yellow oil (yield: 91.2 mg, yield: 27%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08013008B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-5ddb12aeb9914d5cbe75f8432c2f5df8 |
| Source note | uspto-grants-2011_09 |