(Pyridin-4-yl)boronic acid → HCID 67397358, compound

HRID 907045Notes

Reaction equation

HRID 907045 reaction equation
[C:1]([O:4][C@@H:5]1[C@@H:18]([O:19][C:20](=[O:22])[CH3:21])[C@H:17]([O:23][C:24](=[O:26])[CH3:25])[CH2:16][S:15][C@H:6]1[O:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1Br)(=[O:3])[CH3:2].[N:27]1[CH:32]=[CH:31][C:30](B(O)O)=[CH:29][CH:28]=1>>[C:1]([O:4][C@@H:5]1[C@@H:18]([O:19][C:20](=[O:22])[CH3:21])[C@H:17]([O:23][C:24](=[O:26])[CH3:25])[CH2:16][S:15][C@H:6]1[O:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[C:30]1[CH:31]=[CH:32][N:27]=[CH:28][CH:29]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 2734379(Pyridin-4-yl)boronic acidHCID 67398093HCID 67398093, compound

Product 1

HCID 67397358HCID 67397358, compoundYield 65%

Procedure

By carrying out the operation analogously to example 1, starting from 2-bromophenyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside, obtained according to preparation IV, and 4-pyridineboronic acid, the expected product is obtained in the form of a white powder with a yield of 65%.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-93d0ab505ca8472bab7ca99fe2e23fa4
Source dataset
uspto-grants-2011_09
Patent number
US08013010B2

Reaction notes

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