(6-Fluoropyridin-3-yl)boronic acid → HCID 67399736, compound

HRID 907052Notes

Reaction equation

HRID 907052 reaction equation
[C:1]([O:4][C@@H:5]1[C@@H:18]([O:19][C:20](=[O:22])[CH3:21])[C@H:17]([O:23][C:24](=[O:26])[CH3:25])[CH2:16][S:15][C@H:6]1[O:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10](I)[CH:9]=1)(=[O:3])[CH3:2].[F:27][C:28]1[N:33]=[CH:32][C:31](B(O)O)=[CH:30][CH:29]=1>>[C:1]([O:4][C@@H:5]1[C@@H:18]([O:19][C:20](=[O:22])[CH3:21])[C@H:17]([O:23][C:24](=[O:26])[CH3:25])[CH2:16][S:15][C@H:6]1[O:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([C:31]2[CH:32]=[N:33][C:28]([F:27])=[CH:29][CH:30]=2)[CH:9]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 2783397(6-Fluoropyridin-3-yl)boronic acidHCID 25241750HCID 25241750, compound

Product 1

HCID 67399736HCID 67399736, compoundYield 55%

Procedure

By carrying out the operation analogously to example 3, starting from 3-iodophenyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside, obtained according to preparation I, and 6-fluoro-3-pyridineboronic acid, the expected product is obtained in the form of a white powder with a yield of 55%.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-2a3e639f835e47d3abecb50853256b83
Source dataset
uspto-grants-2011_09
Patent number
US08013010B2

Reaction notes

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