HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Iodo-3,5-dimethyl-1,2-oxazole → 2-Chloro-5-(3,5-dimethyl-4-isoxazolyl)phenyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylopyranoside
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Iodo-3,5-dimethyl-1,2-oxazole | HCID 613883 | — |
| Reactant | 5-bromo-2-chlorophenyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylopyranoside | HCID 67395633 | — |
| Product | 2-Chloro-5-(3,5-dimethyl-4-isoxazolyl)phenyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylopyranoside | HCID 67396386 | — |
Reaction Steps
By carrying out the operation analogously to example 58, starting from 5-bromo-2-chlorophenyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside, obtained according to preparation X, and 3,5-dimethyl-4-iodoisoxazole, the expected compound is obtained in the form of a crude product used without further purification in the deacetylation stage.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08013010B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-8939aef6d91b4c52a693b64c6b92bb36 |
| Source note | uspto-grants-2011_09 |