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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 907055Generated: October 31, 2026

4-Iodo-3,5-dimethyl-1,2-oxazole → 2-Chloro-5-(3,5-dimethyl-4-isoxazolyl)phenyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylopyranoside

https://huagongshe.com/reaction/907055

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Iodo-3,5-dimethyl-1,2-oxazoleHCID 613883—
Reactant5-bromo-2-chlorophenyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylopyranosideHCID 67395633—
Product2-Chloro-5-(3,5-dimethyl-4-isoxazolyl)phenyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylopyranosideHCID 67396386—

Reaction Steps

By carrying out the operation analogously to example 58, starting from 5-bromo-2-chlorophenyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside, obtained according to preparation X, and 3,5-dimethyl-4-iodoisoxazole, the expected compound is obtained in the form of a crude product used without further purification in the deacetylation stage.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08013010B2
Source datasetuspto-grants-2011_09
ORD IDord-8939aef6d91b4c52a693b64c6b92bb36
Source noteuspto-grants-2011_09