4-(N-Boc-amino)piperidine → HCID 57551837, compound

HRID 907298Notes

Reaction equation

HRID 907298 reaction equation
[CH:1]1([NH:4][C:5](=[O:30])[C:6]2[CH:11]=[CH:10][C:9]([CH3:12])=[C:8]([C:13]3[CH:14]=[C:15]4[C:20](=[CH:21][CH:22]=3)[C:19](=[O:23])[N:18]([CH2:24][CH:25]3[CH2:27][CH2:26]3)[CH:17]=[C:16]4[CH:28]=O)[CH:7]=2)[CH2:3][CH2:2]1.[NH:31]1[CH2:36][CH2:35][CH:34]([NH:37]C(=O)OC(C)(C)C)[CH2:33][CH2:32]1>>[NH2:37][CH:34]1[CH2:35][CH2:36][N:31]([CH2:28][C:16]2[C:15]3[C:20](=[CH:21][CH:22]=[C:13]([C:8]4[CH:7]=[C:6]([CH:11]=[CH:10][C:9]=4[CH3:12])[C:5]([NH:4][CH:1]4[CH2:2][CH2:3]4)=[O:30])[CH:14]=3)[C:19](=[O:23])[N:18]([CH2:24][CH:25]3[CH2:27][CH2:26]3)[CH:17]=2)[CH2:32][CH2:33]1

Participants

3

Reactant 2

HCID 7238334-(N-Boc-amino)piperidineHCID 57551737HCID 57551737, compound

Product 1

HCID 57551837HCID 57551837, compound

Procedure

The title compound was prepared as a solid by the method of Example 63 using product of Example 59 step iii) and piperidin-4-yl-carbamic acid, tert-butyl ester.

Sources & evidence

ORD record
ord-d658c0e5c09047b79f00a84123db4697
Source dataset
uspto-grants-2011_09
Patent number
US08012979B2

Reaction notes

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