HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethyl-1,3-propanediamine → N-Cyclopropyl-3-(2-(cyclopropylmethyl)-4-((3-(dimethylamino)propylamino)methyl)-1-oxo-1,2-dihydroisoquinolin-6-yl)-5-fluoro-4-methylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethyl-1,3-propanediamine | HCID 7993 | — |
| Reactant | N-Cyclopropyl-3-(2-(cyclopropylmethyl)-4-formyl-1-oxo-1,2-dihydroisoquinolin-6-yl)-5-fluoro-4-methylbenzamide | HCID 57551841 | — |
| Product | N-Cyclopropyl-3-(2-(cyclopropylmethyl)-4-((3-(dimethylamino)propylamino)methyl)-1-oxo-1,2-dihydroisoquinolin-6-yl)-5-fluoro-4-methylbenzamide | HCID 57551742 | — |
Reaction Steps
The title compound was prepared as a solid according to the method of Example 75 step ii) using the product of Example 75 step i) and N1,N1-dimethyl-propane-1,3-diamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08012979B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-191f84a6aa554757899f73959751ef95 |
| Source note | uspto-grants-2011_09 |