HRID907326

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID49761011

未命名化合物

结构：COC(=O)c1ccc(C)c(-c2ccc3c(=O)[nH]cc(C)c3c2)c1

HCID57551764

未命名化合物

PRODUCTS

生成物

结构：COC(=O)c1ccc(C)c(-c2ccc3c(=O)n(Cc4ccc(C5CCN(C(=O)C(F)(F)F)CC5)cc4)cc(C)c3c2)c1

HCID57551829

未命名化合物

PROCEDURE

实验过程

The sub-title compound was prepared by the method of Intermediate 4 using the product of step ii) and the product of Example 93 step ii).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7777812a756b4580b96836179b53a5df
来源数据集: uspto-grants-2011_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08012979B2
来源说明: uspto-grants-2011_09

反应 SMILES

Cl[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:14][CH2:13][N:12]([C:15](=[O:20])[C:16]([F:19])([F:18])[F:17])[CH2:11][CH2:10]2)=[CH:5][CH:4]=1.[CH3:21][C:22]1[CH:31]=[CH:30][C:25]([C:26]([O:28][CH3:29])=[O:27])=[CH:24][C:23]=1[C:32]1[CH:33]=[C:34]2[C:39](=[CH:40][CH:41]=1)[C:38](=[O:42])[NH:37][CH:36]=[C:35]2[CH3:43]>>[CH3:21][C:22]1[CH:31]=[CH:30][C:25]([C:26]([O:28][CH3:29])=[O:27])=[CH:24][C:23]=1[C:32]1[CH:33]=[C:34]2[C:39](=[CH:40][CH:41]=1)[C:38](=[O:42])[N:37]([CH2:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]3[CH2:14][CH2:13][N:12]([C:15](=[O:20])[C:16]([F:19])([F:18])[F:17])[CH2:11][CH2:10]3)=[CH:5][CH:4]=1)[CH:36]=[C:35]2[CH3:43]