Cyclopropylamine → HCID 57551775, compound

Participants

Reaction Steps

A solution of cyclopropylamine (0.18 mL) and the product from step ii) (120 mg) in THF (5 mL) was treated with isopropylmagnesium chloride (2N/THF, 1 mL) and stirred at room temperature for 1 hour. The reaction mixture was quenched with saturated aqueous ammonium chloride (10 mL), and extracted into ethyl acetate (2×10 mL). The organic layer was dried over magnesium sulfate, filtered and evaporated in vacuo. Purification by HPLC gave the title compound as a solid (31 mg).

Provenance & Evidence