(Bromomethyl)cyclobutane → HCID 57551807, compound

HRID 907351Notes

Reaction equation

HRID 907351 reaction equation
[CH:1]1([NH:4][C:5](=[O:24])[C:6]2[CH:11]=[CH:10][C:9]([CH3:12])=[C:8]([C:13]3[CH:14]=[C:15]4[C:20](=[CH:21][CH:22]=3)[C:19](=[O:23])[NH:18][CH:17]=[CH:16]4)[CH:7]=2)[CH2:3][CH2:2]1.Br[CH2:26][CH:27]1[CH2:30][CH2:29][CH2:28]1>>[CH:27]1([CH2:26][N:18]2[CH:17]=[CH:16][C:15]3[C:20](=[CH:21][CH:22]=[C:13]([C:8]4[CH:7]=[C:6]([CH:11]=[CH:10][C:9]=4[CH3:12])[C:5]([NH:4][CH:1]4[CH2:2][CH2:3]4)=[O:24])[CH:14]=3)[C:19]2=[O:23])[CH2:30][CH2:29][CH2:28]1

Participants

3

Reactant 2

HCID 2734658(Bromomethyl)cyclobutaneHCID 25020457N-Cyclopropyl-4-methyl-3-(1-oxo-1,2-dihydro-isoquinolin-6-yl)-benzamide

Product 1

HCID 57551807HCID 57551807, compound

Procedure

The title compound was prepared as a solid according to the method of Example 123 using the product of Example 11 and (bromomethyl)cyclobutane.

Sources & evidence

ORD record
ord-c6da388a71d84cafab791425bed2e022
Source dataset
uspto-grants-2011_09
Patent number
US08012979B2

Reaction notes

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