HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 907370Generated: October 31, 2026
Triethyl phosphite → Diethyl 4-nitrobenzylphosphonate
https://huagongshe.com/reaction/907370
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethyl phosphite | HCID 31215 | — |
| Reactant | 4-Nitrobenzyl bromide | HCID 66011 | — |
| Product | Diethyl 4-nitrobenzylphosphonate | HCID 256065 | 964.2% |
Reaction Steps
A mixture of 4-nitrobenzyl bromide (2.05 g, 0.949 mmol) and triethylphosphite (2.23 g, 1.34 mmol) was heated at 160° C. under a nitrogen atmosphere for 2 h. The excess triethylphosphite was removed in vacuo to give the sub-title compound as a brown oil (2.50 g, 96%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08012967B2 |
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| Source dataset | uspto-grants-2011_09 |
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| ORD ID | ord-25215e1356374678a74b5d0bb5882ac4 |
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| Source note | uspto-grants-2011_09 |
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