HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 57939235, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | HCID 57939239 | HCID 57939239 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57939235 | HCID 57939235 | 99.6% |
Reaction Steps
1 mL of oxalyl chloride (11.5 mmol) and two drops of anhydrous DMF are added under argon to 101 mg of toluene-dried acid 34 (348 μmol) dissolved in 18 mL of anhydrous DCM. The medium is stirred at room temperature for two hours and then concentrated to give 107 mg of a yellow oil, i.e. a yield of 99%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08013132B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-853c9335e21f40ada6594567c0b59f39 |
| Source note | uspto-grants-2011_09 |