HCID 57449634, compound → HCID 57449635, compound

Participants

Reaction Steps

Crude (13) in ethanol was hydrogenated (50 psi H2) over Pd/C (10%, 0.19 g) over night. The reaction was filtered through a bed of Celite. The filtrate was added silica gel, and the solvent was removed under vacuum. Crude product on silica was purified by chromatography on silica gel with 2% saturated ammonia methanol in dichloromethane to give (14) as a light tan foam (423 mg, 1.79 mmol, 73% over 2 steps).

Provenance & Evidence