HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → [(5-Chloro-1H-indol-3-yl)-(2-trifluoromethyl-phenyl)-methyl]-dimethyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 5-Chloroindole | HCID 87110 | — |
| Reactant | o-(Trifluoromethyl)benzaldehyde | HCID 123067 | — |
| Reactant | (2-Trifluoromethyl-benzylidene)-dimethylammonium chloride | HCID 21985293 | — |
| Product | [(5-Chloro-1H-indol-3-yl)-(2-trifluoromethyl-phenyl)-methyl]-dimethyl-amine | HCID 21985295 | — |
Reaction Steps
The preparation was carried out in accordance with general synthesis instructions 4 from 5-chloro-1H-indole and (2-trifluoromethyl-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 2-trifluoromethyl-benzaldehyde and dimethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07091220B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-dc4ce530f30448019d635106dfd1829c |
| Source note | uspto-grants-2006_08 |