HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → Dimethyl-[(2-methyl-1H-indol-3-yl)-(4-trifluoromethyl-phenyl)-methyl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 2-Methylindole | HCID 7224 | — |
| Reactant | 4-(Trifluoromethyl)benzaldehyde | HCID 67996 | — |
| Reactant | (4-Trifluoromethyl-benzylidene)-dimethylammonium chloride | HCID 21985290 | — |
| Product | Dimethyl-[(2-methyl-1H-indol-3-yl)-(4-trifluoromethyl-phenyl)-methyl]-amine | HCID 21985302 | — |
Reaction Steps
The preparation was carried out in accordance with general synthesis instructions 4 from 2-methyl-1H-indole and (4-trifluoromethyl-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 4-trifluoromethyl-benzaldehyde and dimethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07091220B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-4dfdeeb8dda1463f9bf2481d09e0218e |
| Source note | uspto-grants-2006_08 |