HCID 85861734, compound → HCID 86606218, compound

HRID 908176Notes

Reaction equation

HRID 908176 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[S:12][C:11]([NH:13][C:14]3[CH:19]=[N:18][CH:17]=[CH:16][N:15]=3)=[N:10][C:9]=2[CH3:20])=[CH:4][C:3]=1S(N)(=O)=O.BrC(C1C=CC(Cl)=C(S(N)(=O)=O)C=1)C(=O)C.BrC(C1C=CC=C([N+:52]([O-:54])=[O:53])C=1)C(=O)C>>[CH3:20][C:9]1[N:10]=[C:11]([NH:13][C:14]2[CH:19]=[N:18][CH:17]=[CH:16][N:15]=2)[S:12][C:8]=1[C:5]1[CH:6]=[CH:7][CH:2]=[C:3]([N+:52]([O-:54])=[O:53])[CH:4]=1

Participants

4

Reactant 3

HCID 85861734HCID 85861734, compoundHCID 866062162-Chloro-5-[4-methyl-2-(pyrazin-2-ylamino)-thiazol-5-yl]-benzenesulfonamideHCID 866062175-(1-Bromo-2-oxo-propyl)-2-chloro-benzenesulfonamide

Product 1

HCID 86606218HCID 86606218, compound

Procedure

The titled compound is prepared by the same procedure described for the preparation of 33c, replacing 5-(1-Bromo-2-oxo-propyl)-2-chloro-benzenesulfonamide (33b) in this procedure with 1-Bromo-1-(3-nitro-phenyl)-propan-2-one (42a)

Sources & evidence

ORD record
ord-b2170174780045bdbc2523477748d6cb
Source dataset
uspto-grants-2011_09
Patent number
US08017608B2

Reaction notes

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