5-(2-Morpholin-4-yl-ethyl)-[1,3,4]thiadiazol-2-ylamine → HCID 86761402, compound
Reaction equation
[N:1]1([CH2:7][CH2:8][C:9]2[S:13][C:12]([NH2:14])=[N:11][N:10]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.N1C=CC([NH:20][C:21](N)=[S:22])=N1>>[N:1]1([CH2:7][CH2:8][C:9]2[S:13][C:12]([NH:14][C:21]([NH2:20])=[S:22])=[N:11][N:10]=2)[CH2:2][CH2:3][O:4][CH2:5][CH2:6]1Participants
3
Procedure
The titled compound is prepared from 5-(2-Morpholin-4-yl-ethyl)-[1,3,4]thiadiazol-2-ylamine (54b) following the procedure described for (1H-pyrazol-3-yl)-thiourea (35a)
Sources & evidence
- ORD record
- ord-67c7fc879dc34e0caa14c7d944968fea
- Source dataset
- uspto-grants-2011_09
- Patent number
- US08017608B2
Reaction notes
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