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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 908358Generated: October 30, 2026

Dimethylamine → HCID 59262855, compound

https://huagongshe.com/reaction/908358

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant3-(Methylsulfanyl)-4-oxo-4,5,6,7-tetrahydro-2-benzothiophene-1-carbonitrileHCID 2778759—
SolventTetrahydrofuranHCID 8028—
ProductHCID 59262855HCID 5926285545%

Reaction Steps

A solution of 3-methylsulfanyl-4-oxo-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carbonitrile (0.446 g) and dimethylamine (excess) in THF were heated in a sealed tube at 80° C. for 10 days. Aqueous work up and chromatographic purification afforded 0.2 g of 3-dimethylamino-4-oxo-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carbonitrile (45%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08017619B2
Source datasetuspto-grants-2011_09
ORD IDord-9bd9c79ec7f646828492ff414cb0a676
Source noteuspto-grants-2011_09