HCID 67392978, compound → HCID 43451467, compound

Participants

Reaction Steps

730 mg (3.5 mmol) of 5-methoxy-4-nitro-1,3-benzothiazole is solubilized in 50 ml of methanol and 73 mg (10%) of palladium on carbon is added to the reaction mixture which is maintained under stirring under 2.5 bars of hydrogen for 18 hours. The catalyst is filtered out, then the solvent is evaporated off under reduced pressure. 248 mg (yield=40%) of 5-methoxy-1,3-benzothiazol-4-amine is obtained and used in the following stage without other purification.

Provenance & Evidence