HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-4-hydroxyisoquinoline-3-carboxylic acid → 2-[(1-Chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino]-2-methyl-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-4-hydroxyisoquinoline-3-carboxylic acid | HCID 11020520 | — |
| Reactant | Methyl 2-aminoisobutyrate hydrochloride | HCID 13258034 | — |
| Product | 2-[(1-Chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino]-2-methyl-propionic acid | HCID 11449705 | — |
Reaction Steps
Prepared in analogy to Example A-1 a) and b) from 1-chloro-4-hydroxy-isoquinoline-3-carboxylic acid from Example A-2 d) and 2-amino-2-methyl-propionic acid methyl ester hydrochloride; MS-(+)-ion: M+1=308.9 amu.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08017625B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-59df3f7a636b440babdd1721083402e5 |
| Source note | uspto-grants-2011_09 |