HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl D-alaninate hydrochloride → (6-Benzyloxy-1-chloro-4-hydroxy-isoquinoline-3-carbonyl-amino]-propionic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl D-alaninate hydrochloride | HCID 11182647 | — |
| Reactant | 6-Benzyloxy-1-chloro-4-hydroxy-isoquinoline-3-carboxylic acid | HCID 18698135 | — |
| Product | (6-Benzyloxy-1-chloro-4-hydroxy-isoquinoline-3-carbonyl-amino]-propionic acid methyl ester | HCID 86608140 | — |
Reaction Steps
6-Benzyloxy-1-chloro-4-hydroxy-isoquinoline-3-carboxylic acid, 0.33 g, was coupled with D-Alanine methyl ester hydrochloride, 0.150 g, analogously to Example A-1a). 0.205 g of off-white, solid product were obtained, MS-(+)-ion, M+1=415.0 amu.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08017625B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-384b50f5a3af44cd9118b892ae475661 |
| Source note | uspto-grants-2011_09 |