HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Alanine 1,1-dimethylethyl ester → (S)-2-[(4-Benzyloxy-1-methoxymethyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-propionic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Alanine 1,1-dimethylethyl ester | HCID 89016 | — |
| Reactant | 4-Benzyloxy-1-methoxymethyl-7-phenoxy-isoquinoline-3-carboxylic acid | HCID 66712830 | — |
| Product | (S)-2-[(4-Benzyloxy-1-methoxymethyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-propionic acid tert-butyl ester | HCID 66713199 | — |
Reaction Steps
Synthesized from (S)-alanin tert-butyl ester and 4-Benzyloxy-1-methoxymethyl-7-phenoxy-isoquinoline-3-carboxylic acid (Example A-68 c) in analogy to Example A-68 d); MS-(+)-ion: M+23=565.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08017625B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-fefb05d9ffd444d48fbb624ea679471c |
| Source note | uspto-grants-2011_09 |